Essential oil compositions of aerial parts from two species in the Piper (Piperaceae family) genera: Piper lanceaefolium Kunth and Piper hispidum Sw., frequently called deflated (for the anti-inflammatory activity) or cord.Piperaceae leaves were collected in different regions of the Chocó department in northwestern Colombia and identified by botanists from Colombian National Herbarium, where a voucher of each specimen were deposited (No-COL 519993 and No-COL 519969, respectively).The essential oils were obtained by microwaveassisted hydrodistillation (MWHD) and analyzed by gas chromatography-mass spectrometry (GC-MS).The P. lanceaefolium essential oil was sesquiterpenoid type (71.7%).This composition was represented by sesquiterpenes hydrocarbons (58.5%) and by their oxygenated derivates (13.2%); the main compounds were, trans-β β-caryophyllene (11.6%) and germacrene D (10.7%) followed by α α-selinene (7.8%), β β-pinene (5.4%), β β-selinene (4.8%), and α α-cubebene (4.3%).The Piper hispidum essential oil also was sesquiterpene type (74.4%) and oxygenated sesquiterpenes (46.4%) followed by sesquiterpenes hydrocarbons (28.0%).The main compounds were trans-nerolidol (23.6%) and caryophyllene oxide (5.4%) followed by β β-elemene (5.1%), trans-β β-caryophyllene (5.1%), curzerene (4.9%), and germacrene B (4.5%).Trans-β β-caryophyllene presents the higher percentage of the common compounds in the two species' essential oil (11.6% and 5.1% in P. lanceaefolium and P. hispidum, respectively).