This research pretended to find if the consumption of drugs could to adjust a explanation behavioral economics in two rats of laboratory, establishing how the subjects choose between different options of reinforcement with the price each one and income available and how is the substitution between alcohol (etanol) and liquid food (sacharine). The procedure had three phases, began with sheaping of the operant response, after a phase of access free to goods and the last phase of constrain, to evaluate the choice and substitution behavior in labyrinth. This results demonstrated that the rats substituted the sacharine by the etanol, when the prices of sacharine increasing and etanol was in ratio schedule FR1, verifying the work hypothesis.