Additional taxonomical and biological information on Andinopanurgus Gonzalez & Engel, a recently described subgenus of Protandrena Cockerell occurring at mid- and high elevations (1100–3400 m) in the Andes from Venezuela to Peru, is provided. The male of Protandrena maximina Gonzalez & Ruz is described and figured for the first time. New geographical records, an updated key to species, and observations on the foraging behavior of P. guarnensis Gonzalez & Ruz on flowers of cultivated potatoes (Solanum tuberosum L. [Solanaceae]) in central Colombia are also provided.