Transgenderism is an emergent phenomenon. It is necessary not only to evaluate transgenderism, but also all the variables involved in the gender transition process. The aim of the study was to present and analyze psychometric properties of two assessment tools for transgender people. One for Anxiety and the other for Depression. A qualitative construction of the two scales was carried out. Then both were content-validated, and eventually their psychometric properties were tested (Through Cronbach’s Alpha, between-halves correlation, criteria validity and a Factorial Analysis). These scales were applied to 154 people. Both validity and reliability showed good outcomes (for ESANTRA Cronbach’s Alpha .958 and correlation between halves .926 and for ESDETRA Cronbach’s Alpha .967 and correlation between halves 0.958). Criteria validity was high (ESANTRA .782 p <.001). The Exploratory Factorial Analysis only showed one factor in each scale. They had an explanatory variance of 45.71% ESANTRA and 51.55% ESDETRA. ESANTRA and ESDETRA scales seem to be useful for the assessment of anxiety and depression in transgender people.