You have accessJournal of UrologyInfections/Inflammation of the Genitourinary Tract: Prostate & Genitalia1 Apr 2015MP25-16 IMPACT OF RECTAL SWABS ON INFECTIOUS COMPLICATIONS AFTER TRANSRECTAL PROSTATE BIOPSY Carlos Gustavo Trujillo, Mauricio Plata, Juan Ignacio Caicedo, Juan Guillermo Cataño, Diana Castelblanco, and Angela Marcela Mariño Carlos Gustavo TrujilloCarlos Gustavo Trujillo More articles by this author , Mauricio PlataMauricio Plata More articles by this author , Juan Ignacio CaicedoJuan Ignacio Caicedo More articles by this author , Juan Guillermo CatañoJuan Guillermo Cataño More articles by this author , Diana CastelblancoDiana Castelblanco More articles by this author , and Angela Marcela MariñoAngela Marcela Mariño More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.1219AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Transrectal Ultrasonography guided prostate biopsy (PB) is one of the most frequent urologic procedures. Infectious events are the most feared complication. Fluoroquinolones (FQ) have been traditionally used for prophylaxis, but the growing resistance has led to an increase in infectious complications. Strategies to reduce them have been adopted. Rectal swabs (RS) are used to identify FQ-resistant germs and adjust prophylaxis. Our goal is to determine the impact of rectal swabs on infectious complications in these patients. METHODS A retrospective, observational, descriptive cohort study was conducted. All patients subjected to PB between February 2009 and July 2013 were included. The cohort was divided into two groups. Group A is composed by patients without RS and group B by those who had it. The rectal swabs reported the presence of Gram-positive or Gram-negative germs sensitive or resistant to ciprofloxacin, prophylaxis was adjusted according to the result. Patients were monitored with an interview during the first month after PB, infection and hospital admission were registered. Complications were defined as fever, sepsis, severe sepsis, septic shock, bacteraemia, urinary tract infection, prostatitis and epididymitis. The frequency of events such as proportions for categorical variables and averages for continuous variables were determined, as well as normal distribution and parametric statistics to determine inference among them. RESULTS Group A is had 613 patients (52.80%) and B 548 (47.20%). In group B 298 (54.45%) had RS with FQ-sensitive germ and 250 (48.55%) were resistant. Of RS patients with sensitive germ, 49 (16.44%) had received FQ previously, while among those who were resistant, 147 (59.51%) had received them (p>0.0001). Forty patients of the total cohort had infectious complications, 33 of them (5.49%) belonged to group A and 7 (1.28%) to B (p>0.0001). 4.99% of those belonging to group A required hospitalization vs. 1.28% of group B, showing a decrease of 76.68% in infectious complications and 74.34% in hospitalization admissions when implementing RS. CONCLUSIONS Rectal swabs prior to PB and prophylactic antibiotic adjustment according to the results allowed a statistically significant decrease in infectious complications and need for hospitalization. FQ continues to be the drug of choice. Ceftriaxone in a single dose appears as a safe alternative in cases of known resistance. Prior FQ consumption is positively related to resistance in RS. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e291 Peer Review Report Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Carlos Gustavo Trujillo More articles by this author Mauricio Plata More articles by this author Juan Ignacio Caicedo More articles by this author Juan Guillermo Cataño More articles by this author Diana Castelblanco More articles by this author Angela Marcela Mariño More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...