Abstract Sand production in many oil and gas fields is a critical problem that lowers their profitability. The impact can be reduced if the analysis is approached from a multidisciplinary focus that can guide the decision making. Based on the above, this paper focuses on developing a practical methodology, which integrates information from field and laboratory to select and evaluate alternatives of sand exclusion or management, to facilitate making of the best decision from the technical and economic point of view. The study includes: selection of wells and quantification of costs associated with interventions by sanding problems, root cause of the problem of sand production by predictive models, charts of diagnostic and characterization of intervals with sand production, selection of alternatives to sand exclusion or Management, production modeling, technical-economic assessment of selected alternatives, implementation and subsequent evaluation of the work performed. To accelerate the decision making process, the methodology was automated by developing a software tool, which generates standards of the information required for its application, developing of optimal workflow that reduces evaluation times by well over 50%, and creates an environment graphical friendly for the user. The study was conducted in the formations sensitive at sand production of the fields: Lisama, Llanito, Galan, Brisas and Yarigui-Cantagallo in Colombia, and in the wells where the alternative sand exclusion or Management recommendedwas implemented, it was possible to reduce the frequency of interventions in more than 50% and increase their productivity. This paper presents the application results in wells Lisama 166, and Galan 135. Finally, the main findings, conclusions, recommendations and field results obtained in this study are shown.