This article describes a method of instruction using an active learning strategy for teaching stoichiometry through a process of gradual knowledge building. Students identify their misconceptions and progress through a sequence of questions based on the same chemical equation. An infrared device and software registered as the TurningPoint Audience Response System, which can be integrated into Microsoft PowerPoint, is used to instantly retrieve students' answers and provide them with appropriate feedback. The usefulness of breaking down topics in a consistent way and, in particular, emphasizing the subjective interpretation of connectivity and mass relationships in chemistry was evident. Most students felt that the use of the immediate response system combined with cooperative social interactions was positive and contributed to their understanding of the topic.