Abstract A descriptive study of the maxilla and mandible of Cavia is presented. The study includes gross, histological and histochemical investigation of these bones in fetal and adult animals. Particular attention was given to the organization of cellular detail, and vascularity. Tooth development was examined during both intra and extrauterine life. A histochemical study of the ground substance of the cartilage in which these bones develop demonstrated the predominance of acid and neutral mucopolysaccharides.