POPULATION: The Amerindian population of Colombia represents around 1.7% of the population (1,2). They belong to different linguistic families (Chibcha, Tukano, Arawak, Guahibo, Choco, Maku, Karib, and Quechua among others). The Amerindian tribes of Colombia are located in the Amazonian/Orinoquian region, the Northeast, Southwest and Pacific regions of Colombia. Few studies have been carried out for STR variability among Amerindian tribes (3-5). On the other hand, several studies have been performed for STR variability in Caucasian and Afro-Colombian populations (1,2,6-10). We have carried out a study in 7 Amerindian populations named Cubeo (n = 49), Curripaco (n = 32), Desano (n = 28), Tucano (n = 26), Embera (n = 31), Puinabe (n = 77), and Nukak (n = 29) for 6 STR loci (CSF1PO, TPOX, TH01, F13A01, FES/FPS and VWA) to determine allele frequencies and other parameters of forensic importance.