Determine growth and focal points for the development of health economics in Latin America, through the classification methodology proposed by Wagstaff and Culyer. From the results of the development of a literature review of health economics for Latin America in Scopus Database were classified the articles found in twelve groups of different general items, which were proposed by Wagstaff and Culyer in 2012, based on the Williams defining nodes 1989. It was analyzed the changes of production trends, as well as countries and institutions which developed the matter. Production trend changes were found from 1997, where an annual growth of over 50% of production for each year is evident, until 2003. With regard to issues of production about 52% focus on public health, as an item of the twelve general items, followed by the production of 20% in economic evaluation. Universities and institutions are presented with further development of the field, under the creation of courses, masters and specialization, and the creation of research groups. Taking as a reference these studies it is possible to find those areas that can be generated processes use and development of an entire scientific field, such as health economics, and not exhaust the use of a few tools on whims or vices of health systems.