The concept of resilience refers to the interactions between the ecological context and the individual’s capacity to adapt positively to adversity. We analyzed in a marginal context, the relationship between maternal resilience and family functioning to design and implement the intervention and to provide evidence to practice in special education. 76 volunteer mothers took part in this study. All mothers had a child with intellectual disability in a special education school. Two scales were applied to assess maternal resilience and familiar functioning. Statistically meaningful relationships were identified between the dimensions of both instruments; particularly between self-determination as a characteristic of resilience, with five personal and environmental mediators from the same scale, and with the dimensions of the familiar functioning.