Significance Recent research suggests that vector-borne pathogens may frequently manipulate host odors to influence vector attraction. Such effects could have implications for the use of olfactory lures or repellents to disrupt vector transmission, as well as for disease diagnosis. We observed enhanced attraction of mosquitoes to mice infected by the rodent malaria parasite Plasmodium chabaudii during a key period after the subsidence of acute malaria symptoms but during which mice remained highly infectious. This attraction appears to be mediated by an overall elevation of volatile emissions from infected individuals and characteristic changes in the levels of individual compounds. Furthermore, clear differences in the odor profiles of healthy and infected individuals persist throughout the course of infection.