The coherence, directionality and high power in the focal area make laser sources a very convenient source for controlled heating of a sample [1]. The distribution of heat and temperatures produced by laser heating could also be used to control the reaction rates [2]. In this paper we investigate the effects of laser parameters like power, beam size, profile and mode structure on the heating of a cylindrical sample of dipeptide and observe the amount of hydrolysis produced. We model the heating of a solution of dipeptide by a continuous-wave CO2 laser which hydrolyzes and evaporates the solution resulting in production of amino acids.