The efficacy and tolerance of a new anthelmintic drug, Albendazole, was determined in the tratment of 13 children infected with S. stercoralis, in Córdoba, municipality of Buenaventura, Colombia. The study comprising children aged 2-6 years, of both sees, includet administration of 400 mg daily as a single oral dose, for three consecutive days. From a initial prevalence of 16% (n=124), the cure rates were assessed following Baermann's techinique, with samples obtained 7 and 21 days; after the final dose of the drug. A mean cure rate of 76.9% was achieved, with an excellent tolerance to the drug. From this results, it may be suggested that Albendazole should be considered the drug of choice for this of parasite.