The family history in a sportive 49 year old patient with coronary artery disease reveals several members with cardiovascular events. The diagnosis of dyslipidemia could be made in all the patient's children. Genetic analysis of the patient shows a heterozygous mutation of the apolipoprotein B-100 genotype. An accurate family history and screening for cardiovascular risk factors are mandatory in all patients with a history of premature coronary artery disease.
