The crystal structure of a per­acetyl­ated glu­cosyl ester of kaurenic acid, (4α)-kaur-16-en-18-carbonyl 2,3,4,6-tetra-O-acetyl-α-d-gluco­pyran­oside, C34H48O11, is reported. The synchrotron X-ray diffraction experiment showed that the glu­cosyl moiety adopts an α-perpendicular orientation with respect to the plane of the kaurenic acid. This conformation would allow the sugar hydroxyl groups, one unprotected, to interact with solvent or with biological membranes, enhancing its in vitro activity against murine melanoma in mice.