To describe the distribution pattern and the clinical features of uveitis in two ophthalmology referral centres in Colombia.This was a retrospective study in which clinical records of patients attending the centres between 1996 and 2006 were systematically reviewed. Data were analysed and compared with previous reports.Uveitis was found in 693 patients: 335 men (48.3%) and 358 women (51.7%). The mean age for the first presentation was 31.7 +/- 18.3 years. Unilateral (73.4%), acute (68.3%), posterior (35.9%) and non-granulomatous (90.6%) were the most common types of uveitis found in the sample. Toxoplasmosis was the most frequent cause in this study followed in order by idiopathic and toxocariasis. Vogt-Koyanagi-Harada, Behçet's disease, sarcoidosis and white dot syndromes were less common. Some causes such as systemic lupus erythematosus and tuberculosis were extremely rare. Presumed ocular histoplasmosis, onchocerciasis and Lyme disease were absent.The results of this study provide the first report of clinical patterns for uveitis in Colombia. This study will enhance awareness of uveitis, and data should assist in the development of public health policies in our population for the improvement of patient outcomes.