The reproductive cycle, recruitment and maturity size of the mangrove cockle Anadara tuberculosa was studied between August 2009 and August 2010 at the 4 departments of the Colombian Pacific coast.Biological samples were collected on three 50 m 2 plots of each region following the traditional method of capture.To determine the state of sexual development, monthly macro and microscopy (using standard histological techniques) observations were performed.The reproductive cycle was divided in 4 stages, resting, development, maturity and spawning.Spawning events were evident throughout the study period, with higher reproductive activity between December and March, and a second short event between June and August.The average maturity size (46.68 ± 9.29 mm) and mean first maturity size (43.50 mm) are below the minimum legal size of capture (50.00 mm) in Colombia.Temporal variation of reproductive activity and recruitment shows no evidence of sexual maturity synchrony in the Colombian Pacific, important for the establishment of management strategies of the resource.Three percent of hermaphroditism was found which is considered protandric due to the imbalance of sex ratio between females and males (2.46:1) and size difference between sexes.