It is described a leptospirosis case produced by Lep- tospira pomona in a 20 years old woman working in a rice mill, and characterized by a sindrome of hepatic and renal insufficiency. The disease was manifested by discomfort,anorexia, vomiting, fever, diarrhea, jaundice and subconjuntivalbleeding. Clinical tests shawed disturbances in the levels of Creatinine, blood chlorine, alkaline phosphatase and direct bilirrubin indicating a renal and hepatic dysfunction. Hematicdisturbances in erythrocyte sedimentation rate, hemoglobin, haematocritand leukocytosis showed the infection adn anemia produced by L. pomonain the patient. It is called the attetion to make always a differentialdiagnosis in all suspicious cases of leptospirosis specially when the epidemiological background and symtoms make suspect a disease produced by Leptospiraspecies.