Abstract A special engineering methodology was developed to understand the complexity of formation damage mechanism currently affecting the well productivity of the oil fields being operated by SOP (Superintendencia de Operaciones Putumayo) Ecopetrol. The initial stage of this study involved the characterization and analysis of reservoir fluids samples taken along the time during different exploitation stages. The analyzed data was processed through specialized software to identify formation damage associated with both organic and mineral scales. Simultaneously a second stage was developed to determine and quantify the influence of production parameters on both fines migration and water production. The data obtained during the previous stages were properly combined to generate a comprehensive formation damage model. Nodal system analysis, material balance, reservoir fluids characterization, and mineral/organic scale models and correlations were finally combined to identify and quantify the main formation damage mechanisms taking place in SOP′s fields. Once the main formation damage mechanisms were identified and quantified then an extensive lab job was performed. This lab study determined the Best In Class (BIC) fluids required to dissolve and mitigate the formation damage. The combination of formation damage model with lab data allowed designing an optimized treatment schedule by each well producing in SOP fields. Finally, an economical study was involved in the study in order to help in well prioritization to start the stimulation and inhibition campaign for SOP field. A 3D simulation of certain formation damage mechanism was included as the final stage in this study. It was very important, especially when optimizing the stimulation-inhibition designs in those wells in which local grid refinement is required to better understanding of certain critical formation damage parameters. The final list of well prioritization was optimized and stimulation-inhibition campaign for SOP fields was finally outlined to be started during the second semester of 2011.