Logotipo ImpactU
Autor

Constituents of Oxandra cf. xylopioides with Anti-inflammatory Activity

Acceso Cerrado
ID Minciencias: ART-0000112160-131
Ranking: ART-ART_A1

Abstract:

A new triterpenoid (1) derived from 24-methylcycloartanol was isolated from the leaves of Oxandra cf. xylopioides. An unusual structure of the new compound was assigned as 1, for which the name berenjenol is proposed, on the basis of the spectroscopic data of the natural product and of its derivatives 2 and 3. The leaves also afforded the known monoterpene isoespintanol (4). Compounds 1 and 4 significantly reduced the paw edema induced by carrageenan by 64% and 43%, at 3 h, respectively. Moreover, 4 reduced IL-1β production by 72% at 100 μM and reduced IL-1β mRNA synthesis.

Tópico:

Natural product bioactivities and synthesis

Citaciones:

Citations: 33
33

Citaciones por año:

Altmétricas:

Paperbuzz Score: 0
0

Información de la Fuente:

SCImago Journal & Country Rank
FuenteJournal of Natural Products
Cuartil año de publicaciónNo disponible
Volumen70
Issue5
Páginas835 - 838
pISSNNo disponible
ISSN1520-6025

Enlaces e Identificadores:

Artículo de revista