Pd over TiO2 (sol−gel and Hombikat uv-100) slurries with and without binders have been deposited on square-channel cordierite honeycombs, and vibration, heat, and abrasion resistance of washcoated minimonoliths have been evaluated. Activity tests were carried out in a microreactor operated at differential conditions. Fresh and used catalyst samples were characterized by elemental analysis, XRD, BET, H2-chemisorption, H2-TPR, NH3-TPD, UV−vis, and SEM in order to assess not only the properties but also the homogeneity of catalyst layers. The results show that washcoat loading and catalytic performance are affected by the kind of binder used in the slurry. Washcoat differences are also found regarding vibration, heat, and abrasion resistance.