Cyclospora cayetanensis infection. Updated review a propos of three cases of traveler's diarrheaHuman infection by Cyclospora cayetanensis, namely cyclosporiasis, can cause a wide range of symptoms in immunocompetent patients, from mild to severe diarrhea.Immunocompromised patients can present with chronic diarrhea and it has been recognized as a cause of traveler's diarrhea.We report three patients who traveled from Chile to Peru, who presented upon returning with prolonged traveler's diarrhea.A literature review about cyclosporiasis is presented, with emphasis on the clinical, epidemiological, diagnostic and therapeutic aspects of this disease.