Health professionals have high exposure to psychosocial risk factors at work. Studies mainly refer to physicians and nurses; references are scarce in terms of other professionals in the area, auxiliary and administrative personnel at health institutions that share attention’s responsibility towards users and their families. This study measures the exposure levels to psychosocial risk factors that may affect professionals and employees at a rehabilitation foundation in Cali. This is a descriptive study, with 59 participants, that assessed said exposure level with the ISTAS 21 Method. The research found, in most professionals and employees, a psychosocial risk factors’ exposure level that may be adverse for health, in terms of psychological demands and job insecurity. Discoveries suggest that health care-taking determines a series of demands that may affect all personnel at health institutions and not only those responsible for the patient’s care assistance.