El presente trabajo se enfoco en desarrollar un proceso para la eliminacion del gas estireno, un contaminante organico generador de malos olores en el aire. Se construyo un sistema de biofiltracion en el cual seemplearon bacterias del tipo Pseudomona aeruginosa y Escherichia coli adheridas a un soporte de piedra pomez.Se contamino aire con estireno en concentraciones por encima del estandar norteamericano (TLV 40ppm, ACGIH 2002), para simular una atmosfera laboral de alto riesgo a la salud. A fin de evaluar la eficiencia delsistema, se midieron directamente las concentraciones de estireno a la entrada y a la salida, utilizando unmedidor de vapores organicos. Durante los primeros dias se obtuvieron remociones por encima del 55%, para un promedio de 5 mediciones diarias, durante un periodo de 10 dias. El sistema se fue estabilizando progresivamente durante la fase inicial, por lo que la remocion no fue la optima. A partir del dia 8 se alcanzaronremociones promedio por encima del 70% y remociones especificas superiores al 90%.El soporte de piedra pomez demostro ser una buena alternativa, facilitando la formacion de una biopelicula; la rapida saturacion de sus microporos permitio garantizar la baja adsorcion del compuesto organico en el medio (piedra pomez + microorganismos), confirmando un autentico proceso de biodegradacion. Abstract: This work was focused on developing an elimination process of styrene, an organic compound generating complex odors in air, through the design and construction of a biofiltration system, utilizing bacteria of the Pseudomona aeruginosa and Escherichia coli types stuck on a pumice stone support. Air was contaminated with styrene, in concentrations above the American Standard (TLV 40 ppm,ACGIH Worldwide, 2002), to simulate a hazardous work environment to the human health. To evaluate the efficiency of the system, the contaminated inlet air as well as the outlet flow were analyzed by taking directstyrene concentrations measurements with an organic vapor meter. Initially, the results obtained from thestyrene degradation were above 55%, for a five-daily-sampling average during 10 days. This percentage was aconsequence of the progressive stabilization process of the system within the first days, so the removal was low.However, average removals above 70% and punctual removals above 90% were reached after the eighth day.The pumice stone support demonstrated to be a good alternative to improve biofilm formation; the rapid micropore saturation guaranteed low adsorption of the organic compound and confirmed the elimination of styrene via biodegradation .