Based on a qualitative research, a didactic multimedia educational materials for chemistry, was developed which integrates the teaching model of problem solving, learning difficulties and the media in order to support the process of teaching and learning chemistry. In the design, development and implementation software was used Flash CS5 and applied the methodology on Software Engineering Education (SEE) with evaluation by users for pilot testing, field testing and evaluation by an expert, chemical content and digital materials design expert. The material produced multimedia interactivity promotes teacher-student-contained and self-learning of chemistry, according to the high percentage of satisfaction rated by freshmen agricultural engineering from the University of the Llanos in the second academic period 2010 and the evaluation by an expert in the design of digital material.