This research shows the importance of phenomenological experience, as well as the need of approaching the problem of conscience and new alternatives for the study of the mind. The reference point is Francisco Varela. Enactive theory is presented within the panorama of philosophy of the mind, highlighting its more critical aspects. From this point of view, the concept of enaction is developed, overcoming representational theory. The problem of the Me is focused from the enactive theory and the Madhyamika theory. At the end, the author reflects on the possible suspension of the Me in some transformation practices.