En este articulo se describe el caso clinico de un canino criollo de diez anos de edad a quien se le diagnostico melanoma maligno en cavidad oral por medio de un estudio hispotalogico. Se implemento un manejo medico mediante cirugias y quimioterapias, mejorando su estado general y previniendo la aparicion de metastasis en organos importantes como los pulmones. Abstract In this article is described the clinic case of the native canine, of ten years old who was diagnosed malignant melanoma in oral cavity, by mean of a histopathologyc study. It was implemented a medical management through surgeries and chemotherapies, getting better its general state and preventing the appearing of metastasis in important organs such lugs.