A retrospective analysis about the dynamic of People Trafficking crime from 2007 to 2012 was made in Caldas. The intention was to identify some critical aspects regarding protection measures and their impact on the effectiveness of the law in the penalization of this crime. Thus, an analysis of the primarily sources was carried out, such as liability uttered judgments, competent statistic of the expert agencies in the investigation and prosecution of Human Trafficking crime. Results showed that even though the authorities consider this crime in a wide and modern context including all of its forms of behavior in Caldas, all the cases that were investigated and prosecuted refer to prostitution as a wicked activity incompatible with dignity and the value of the person. Similarly, they refer to the inclusion of human beings to prostitution mainly minors of both sexes and adult women either willingly or as a result of strength, deception or coercion to be forced national level or as a result in of the smuggling of migrants. Any case or process already begun by the judicial authorities concerning trafficking with other different purposes such as domestic work, servile marriage or forced labor was not found. To conclude, the effectiveness of Colombian criminal law as a means of control and prevention of the Human Trafficking is inefficient.