In this study, a Spanish version of the ERI questionnaire was tested in Colombia. Cross-sectional studies were performed among two groups of teachers (251 and 318), 294 nurses, 281 bus drivers, and two mixed occupational groups (661 and 117 participants). The internal consistency and the factorial, concurrent and predictive validity of the instrument were examined. Mean values and standard deviations of the Colombian workers were compared to each other and then to averages available for similar workers from two other countries. Based on the results on six groups of Colombian workers presented in this article, it can be said that the Spanish version of the ERI Questionnaire has show to be a satisfactory measurement instrument of the psychosocial risk factors at work in Colombia.