Our research is based a measurement made to a selection of Twitter users greater “prominence” in Latin America and the Middle East, as well as an sample of the messages posted by them. The data were taken during the first half of 2012, from a quantitative investigation of court, and was carried out to analyze for characterize the profiles and messages posted by users before mentioned, according to regions taken into consideration, in addition to providing us the identification of factors affecting significantly in the gain and loss of followers of these users.