The objective of this study was to determine the relationship between obesity, body image dissatisfaction, teasing perception, and attitude towards physical appearance and the influence of these variables on life satisfaction. Using a non-experimental, cross-sectional design, a path analysis was performed on data from 328 obese patients in Venezuela. The results showed that obesity doesn’t predict life satisfaction. This was predicted by teasing perception and body image dissatisfaction. Attitude towards physical appearance has an indirect effect on life satisfaction in obese patient, behaving like mediator variables. The results suggest what makes obese people dissatisfied is an interiorized aesthetic ideal which is unreachable. This is expressed by emotional susceptibility to teasing and dissatisfaction with body image.