Abstract Andean orogenic processes controlled the spatial and temporal distribution of the magmatic and sedimentary record. This contribution integrates new U/Pb zircon ages, heavy mineral analyses and biostratigraphic constraints from the Neogene sedimentary record of the fore‐arc and intra‐arc basins and volcano‐plutonic rocks of southwestern Colombia, to reconstruct these orogenic processes. The results reveal continuous arc magmatism since the Late Oligocene, with a major post‐Middle Miocene magmatic peak and exhumation. When integrated with other geological constraints, the tectonic evolution of the margin includes Eocene‐Oligocene oblique convergence with limited magmatic activity, followed by the initiation of a Late Oligocene‐Early Miocene arc that migrated to the east in the Middle Miocene, when it experienced a major increase in magmatic activity, crustal deformation, exhumation and thickening. This orogenic evolution is related to the shallowing of the slab dip due to the subduction of the Neogene Nazca Plate.