The survival of MSMEs is important for the stability of any economy, due to its capacity for employment, contribution to GDP and economic diversification. Part of the success of surviving is linked to its accounting and financial management processes. This article exposes a sectoral analysis of the enterprises under study, about their financial information management practices and their use in decision making. For this purpose, a descriptive research is developed with the objective of characterizing the accounting and financial management of the MSMEs in eastern Antioquia (Colombia), a potential scenario of national and international integration; applying a survey of 42 questions to a sample of 379 MSMEs. The findings point to that many of the decision-making schemes of MSMEs in eastern Antioquia have been carried out in good form, but the accounting and financial management processes are still incipient, addressing the compliance, without adopting clear procedures for integrating this information into the decision-making processes.