The data on inclusions and exclusions of paternities carried out by the Forensic Genetics of the Public Ministry in Honduras are presented. All these paternities verifications have been included. The results show that there is an exclusion of about one-third of all official filial paternity tests, which has remained constant in proportion between the years 2018 to 2022; the data used corresponds to the totality registered in the Public Ministry, carried out throughout the territory of Honduras in the indicated years, for a total sample of 321 filial paternity test records. Genetic testing has been developed with sequenced, court-ordered, or civil samples where filial parentage is desired. The exclusion rates are like other countries in the region; it is a pending task to determine the associated cultural element for the high variability in the different countries of the exclusion rates. Keywords: Paternity; forensic medicine service; polymerase chain reaction; filial parenthood exclusion; DNA sequencing