The construction industry was proclaimed by the Colombian government as one of the driving forces of the national economy. This research studies the internationalization process of Antioquia’s building materials sector in terms of entry modes used, type of products, country of destination, and use of trade agreements. In order to achieve this objective, a descriptive study was developed, using primary and secondary sources of information. The results show that the main building material companies in Antioquia have had unassertive internationalization processes, strongly dependent on exports to natural and traditional markets such as Venezuela, Ecuador, and Peru. However, the article highlights cases of companies with extensive national and international experience which have implemented riskier entry modes such as acquisitions or strategic alliances.