Inventory of Suicide Orientation - ISO 30, it is a self-report scale that measures risk of adolescents suicideorientation. Although the risk of adolescents suicide is on the public agenda in Colombia actually, there is no studyto analyze the psychometric properties of ISO 30, and for this reason, the present study is conducted with a randomsample of 604 adolescent students (48% were male and 52% female with an average age of 14 and a deviation of 1.9years). Methods: A confirmatory factor analysis was performed; reliability is checked by the Cronbach's alpha andcorrelation item-subconstruct to which it belongs; The test-retest reliability and concurrent validity with the RFL-Avalidated scale in Colombia with teenage school people is verified. AMOS 16.0 and SPSS version 20.0 for dataprocessing was used. Results: this population was confirmed in the same factorial structure of the original scale; sodoes the internal consistency for the 30 items and the correlation of each item with its own subconstruct: socialisolation and marginalization, low self-esteem, inability to manage emotions, suicidal ideation and hopelessness.Conclusion: The Inventory of Suicide Orientation - ISO 30 Spanish version, is a useful questionnaire and appropriateto diagnose the risk of suicidal orientation (which is a prelude to suicidal idea) in the adolescents students people inMedellin city.