Introduction: Candida albicans is the most frequently isolated yeast from the oral cavity of HIV-infected individuals. The use of fluconazole has increased thenumber of resistant or less-sensitive Candida species different from C. albicans, to this antifungal agent. Objective: To establish the Candida species present in the oral cavity of HIV-infected individuals at a hospital in Cali (Colombia), their population densities, and the susceptibility to fluconazole of species different from C. albicans.  Materials and methods: Samples were cultured in CHROMagar Candida and the number of colony forming units (CFU) was counted. Yeast identification was done with API 20C Aux, and the susceptibilitytests to fluconazole, by Etest. Results: 230 patients were studied, and 202 isolates were obtained: 106 single and 96 mixed. C. albicans predominated, followed by C. dubliniensis and C.glabrata. Candida species other than C. albicans predominated in counts lower than 400 CFU/mL. Susceptibility study to fluconazole of species different fromC. albicans showed that 14 (40 %) of the isolates were susceptible dose-dependent and 7 (20 %), resistant. Conclusion: In the studied population, the oral cavity was colonized by non-wild type isolates that represent a risk for the development of oropharyngeal candidiasis resistant to fluconazole treatment.